[Go to this article.]

Figure 3
Osx-positive Op cells do not respond to Bzb, while Osx-negative MSCs respond to Bzb in vitro. Ops were recovered from the compact bone of Osx-GFP mice by isolation of CD45^–GFP⁺ cells. CD45^–GFP⁺ Ops plated in vitro showed no change in collagen I clusters, while CD45^–GFP^– MSCs isolated from the same mice showed an increase (arrows). *P < 0.05; n = 4. Original magnification, ×100.