Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice
J. Clin. Invest. Siddhartha Mukherjee, et al. 118:491 doi:10.1172/JCI33102 [Go to this article.]

Figure 4
Bzb acts on hMSCs. (A) hMSCs (CD105⁺CD73⁺CD45^–) were subjected to Bzb in vitro, and API was assessed after 6 days in culture. API measurements revealed an increase in activity with 0.5, 1, and 2 nM Bzb. *P = 0.001; n = 10. (B) Alizarin red staining was increased upon Bzb treatment. **P = 0.002; n = 5 fields. (C) Adipocytes (oil red O–positive cells) were decreased. Original magnification, ×100. ^†P = 0.03; n = 4 fields.