A contrast agent recognizing activated platelets reveals murine cerebral malaria pathology undetectable by conventional MRI
J. Clin. Invest. Constantin von zur Muhlen, et al. 118:1198 doi:10.1172/JCI33314 [Go to this article.]

Figure 2
In vitro MPIO platelet binding. (A–C) Nonactivated or ADP-activated platelets were incubated with LIBS-MPIO (A), control-MPIO (B), or nonfunctionalized MPIOs (C). Note the presence of LIBS-MPIO binding on the surface of the activated platelets on the thrombus, which was not observed on nonactivated platelets or with the control MPIO or nonfunctionalized MPIO.