C4d staining of pulmonary allograft biopsies: an immunoperoxidase study
WD Wallace, EF Reed, D Ross, CR Lassman… - The Journal of heart and …, 2005 - Elsevier
BACKGROUND: The role of antibody-mediated/humoral rejection in lung allografts is not
fully elucidated. In other organ systems, deposition of a specific complement product, C4d, is
a sensitive and specific marker for humoral rejection. C4d can be evaluated in tissue
biopsies by immunofluorescence or light microscopic immunohistochemical staining
techniques. Using immunohistochemical staining techniques we sought to determine
whether there was any specific staining pattern for C4d in lung allograft biopsies with or …
fully elucidated. In other organ systems, deposition of a specific complement product, C4d, is
a sensitive and specific marker for humoral rejection. C4d can be evaluated in tissue
biopsies by immunofluorescence or light microscopic immunohistochemical staining
techniques. Using immunohistochemical staining techniques we sought to determine
whether there was any specific staining pattern for C4d in lung allograft biopsies with or …