Stress-related changes in proinflammatory cytokine production in wounds
R Glaser, JK Kiecolt-Glaser, PT Marucha… - Archives of general …, 1999 - jamanetwork.com
Background Several recent studies have shown that stress markedly delays wound healing.
This study assessed the relationship between psychological stress and the secretion of
proinflammatory cytokines at an actual wound site, providing in vivo data on the
development of local immune responses that are central in the early stages of wound repair.
Methods To study the dynamics of inflammation, skin blisters were induced on the forearm of
36 women (mean age, 57 years) by suction. After the blister roofs were removed, a plastic …
This study assessed the relationship between psychological stress and the secretion of
proinflammatory cytokines at an actual wound site, providing in vivo data on the
development of local immune responses that are central in the early stages of wound repair.
Methods To study the dynamics of inflammation, skin blisters were induced on the forearm of
36 women (mean age, 57 years) by suction. After the blister roofs were removed, a plastic …