In vitro responses of detrusor smooth muscle to stretch and relaxation
AE Finkbeiner - Scandinavian Journal of Urology and Nephrology, 1999 - Taylor & Francis
In vitro studies subjecting detrusor smooth muscle to stretch and relaxation support the
concept that bladder tonus and accommodation result from physical properties of the
bladder wall and are not dependent upon neural activity. The properties of automaticity,
hysteresis and length/tension relationships of smooth muscle seen clinically and in vivo are
also seen in vitro.
concept that bladder tonus and accommodation result from physical properties of the
bladder wall and are not dependent upon neural activity. The properties of automaticity,
hysteresis and length/tension relationships of smooth muscle seen clinically and in vivo are
also seen in vitro.
Responses of detrusor smooth muscle to stretch and relaxation: in vitro study
AE Finkbeiner, PD O'Donnell - Urology, 1990 - Elsevier
An in vitro model subjecting bladder muscle strips to continuous stretch relaxation evaluated
the properties of passive muscle length and tension. Tension generated as a strip was
stretched or relaxed was found to be stretch-rate dependent. The primary influence of stretch
rate on muscle tension is by alteration of muscle length; however, stretch and relaxation
rates do influence the inherent smooth muscle properties of hysteresis, stress-relaxation,
and adaptation. The characteristic filling curve to the point of bladder contraction seen …
the properties of passive muscle length and tension. Tension generated as a strip was
stretched or relaxed was found to be stretch-rate dependent. The primary influence of stretch
rate on muscle tension is by alteration of muscle length; however, stretch and relaxation
rates do influence the inherent smooth muscle properties of hysteresis, stress-relaxation,
and adaptation. The characteristic filling curve to the point of bladder contraction seen …