[HTML][HTML] A naturally processed rat major histocompatibility complex class I-associated viral peptide as target structure of borna disease virus-specific CD8+ T cells
The first naturally processed peptide synthesized by a virus and recognized by classical
CD8+ T cells in association with the RT1. A l major histocompatibility complex class I
molecule of the Lewis rat is reported. Borna disease virus-specific CD8+ T cells recognize
syngeneic target cells pulsed with peptides extracted from Borna disease virus-infected
cells. The predicted peptide sequence ASYAQMTTY from the viral p40 protein coeluted with
the cytotoxic T-lymphocyte-reactive fraction was identified among natural ligands by tandem …
CD8+ T cells in association with the RT1. A l major histocompatibility complex class I
molecule of the Lewis rat is reported. Borna disease virus-specific CD8+ T cells recognize
syngeneic target cells pulsed with peptides extracted from Borna disease virus-infected
cells. The predicted peptide sequence ASYAQMTTY from the viral p40 protein coeluted with
the cytotoxic T-lymphocyte-reactive fraction was identified among natural ligands by tandem …