Two populations of Ia-like molecules on a human B cell line.
LA Lampson, R Levy - Journal of immunology (Baltimore, Md.: 1950 …, 1980 - journals.aai.org
LA Lampson, R Levy
Journal of immunology (Baltimore, Md.: 1950), 1980•journals.aai.orgEvidence is presented for two populations of Ia-like molecules on the human B cell line Raji.
Two monoclonal antibodies, L203 and L227, are described. Both recognize nonpolymorphic
determinants on B cell antigens. Both immunoprecipitate 34,000-and 28,000-dalton material
from 125I-labeled extracts of Raji, but L227 precipitates 25,000-dalton material as well.
Immunodepletion experiments confirm that the antibodies react with two different
populations of molecules.
Two monoclonal antibodies, L203 and L227, are described. Both recognize nonpolymorphic
determinants on B cell antigens. Both immunoprecipitate 34,000-and 28,000-dalton material
from 125I-labeled extracts of Raji, but L227 precipitates 25,000-dalton material as well.
Immunodepletion experiments confirm that the antibodies react with two different
populations of molecules.
Abstract
Evidence is presented for two populations of Ia-like molecules on the human B cell line Raji. Two monoclonal antibodies, L203 and L227, are described. Both recognize nonpolymorphic determinants on B cell antigens. Both immunoprecipitate 34,000- and 28,000-dalton material from 125I-labeled extracts of Raji, but L227 precipitates 25,000-dalton material as well. Immunodepletion experiments confirm that the antibodies react with two different populations of molecules.
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