[3] Immunoglobulin A (IgA)
J Mestecky, M Kilian - Methods in enzymology, 1985 - Elsevier
Publisher Summary This chapter provides an overview of immunoglobulin A (IgA). IgA is
found in adult human serum in concentrations that range from 66 to 344 mg/dl. In secretions
IgA represents, under normal conditions, the predominant immunoglobulin isotype. Serum
IgA occurs mostly in the form of monomeric (6.5-7 S) molecules composed of two H (MW=
53,000) and two L (MW= 22,500) chains. A minor portion of the IgA present in sera of normal
individuals is found in polymeric form with monomers connected by disulfide bonds and …
found in adult human serum in concentrations that range from 66 to 344 mg/dl. In secretions
IgA represents, under normal conditions, the predominant immunoglobulin isotype. Serum
IgA occurs mostly in the form of monomeric (6.5-7 S) molecules composed of two H (MW=
53,000) and two L (MW= 22,500) chains. A minor portion of the IgA present in sera of normal
individuals is found in polymeric form with monomers connected by disulfide bonds and …