The in vitro generation of dendritic cells (DCs) from either blood or bone marrow has been
accomplished for humans and a number of other species. This ability has facilitated the
opportunity to test the efficacy of DC vaccines in various tumor models. The cottontail rabbit
papillomavirus (CRPV) model is the most clinically relevant animal model for human
papillomavirus (HPV)-associated carcinogenesis. The CRPV model has been used to test
various preventative and therapeutic vaccination strategies, and the availability of rabbit …