[HTML][HTML] Molecular cloning and functional characterization of a novel CC chemokine, stimulated T cell chemotactic protein (STCP-1) that specifically acts on activated T …
M Chang, J McNinch, C Elias, CL Manthey… - Journal of Biological …, 1997 - ASBMB
A novel human chemokine STCP-1 (stimulated T cell chemotactic protein) was isolated from
an activated macrophage cDNA library. The chemokine has four cysteines positioned in a
manner that identifies STCP-1 as a member of the CC chemokine family. The amino acid
sequence shows 34% identity with RANTES. The gene consists of 3 exons and 2 introns
with the position of intron/exon boundaries similar to that of RANTES. The gene is expressed
as a 3.4-kilobase transcript on lymph node, thymus, and Appendix. STCP-1 induces Ca 2+ …
an activated macrophage cDNA library. The chemokine has four cysteines positioned in a
manner that identifies STCP-1 as a member of the CC chemokine family. The amino acid
sequence shows 34% identity with RANTES. The gene consists of 3 exons and 2 introns
with the position of intron/exon boundaries similar to that of RANTES. The gene is expressed
as a 3.4-kilobase transcript on lymph node, thymus, and Appendix. STCP-1 induces Ca 2+ …