Risk for myopathy with statin therapy in high-risk patients
CM Ballantyne, A Corsini, MH Davidson… - Archives of internal …, 2003 - jamanetwork.com
Emerging data suggest that the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA)
reductase inhibitors (statins) offer important benefits for the large population of individuals at
high risk for coronary heart disease. This population encompasses a sizable portion of
individuals who are also at high risk for drug-drug interactions due to their need for multiple
medications. In general, statins are associated with a very small risk for myopathy (which
may progress to fatal or nonfatal rhabdomyolysis); however, the potential for drug-drug …
reductase inhibitors (statins) offer important benefits for the large population of individuals at
high risk for coronary heart disease. This population encompasses a sizable portion of
individuals who are also at high risk for drug-drug interactions due to their need for multiple
medications. In general, statins are associated with a very small risk for myopathy (which
may progress to fatal or nonfatal rhabdomyolysis); however, the potential for drug-drug …