Clinically relevant concentrations of β2-adrenergic agonists stimulate maximal cyclic adenosine monophosphate-dependent airspace fluid clearance and decrease …
DF McAuley, JA Frank, X Fang… - Critical care medicine, 2004 - journals.lww.com
Objective: To determine whether clinically relevant airspace concentrations of β 2-
adrenergic agonists stimulated maximal alveolar fluid clearance rates and to determine
whether β 2 agonist therapy decreased pulmonary edema in experimental acute lung injury.
Design: Prospective randomized laboratory investigation. Setting: University-affiliated
laboratory. Subjects: Sprague Dawley rats. Interventions: Dibutyryl cyclic adenosine
monophosphate (cAMP), salmeterol, albuterol, and isoproterenol in normal rat lung …
adrenergic agonists stimulated maximal alveolar fluid clearance rates and to determine
whether β 2 agonist therapy decreased pulmonary edema in experimental acute lung injury.
Design: Prospective randomized laboratory investigation. Setting: University-affiliated
laboratory. Subjects: Sprague Dawley rats. Interventions: Dibutyryl cyclic adenosine
monophosphate (cAMP), salmeterol, albuterol, and isoproterenol in normal rat lung …