HIV-based vectors: preparation and use
A Follenzi, L Naldini - Gene Therapy Protocols, 2002 - Springer
Gene Therapy Protocols, 2002•Springer
The development of gene transfer vectors from lentiviruses, such as the human
immunodeficiency virus 1 (HIV-1), has opened exciting perspectives for the genetic
treatment of a wide array of inherited and acquired diseases, because of their ability to
achieve the efficient delivery, integration, and long-term expression of transgenes into
dividing and nondividing cells both in vitro and in vivo.
immunodeficiency virus 1 (HIV-1), has opened exciting perspectives for the genetic
treatment of a wide array of inherited and acquired diseases, because of their ability to
achieve the efficient delivery, integration, and long-term expression of transgenes into
dividing and nondividing cells both in vitro and in vivo.
Abstract
The development of gene transfer vectors from lentiviruses, such as the human immunodeficiency virus 1 (HIV-1), has opened exciting perspectives for the genetic treatment of a wide array of inherited and acquired diseases, because of their ability to achieve the efficient delivery, integration, and long-term expression of transgenes into dividing and nondividing cells both in vitro and in vivo.
Springer