Erythropoietin concentrations and neurodevelopmental outcome in preterm infants

R Bierer, MC Peceny, CH Hartenberger, RK Ohls - Pediatrics, 2006 - publications.aap.org
OBJECTIVE. Erythropoietin therapy is effective in decreasing transfusions to varying
degrees in preterm infants. Recent animal studies using erythropoietin doses to achieve
serum concentrations> 1000 mU/mL report neuroprotective effects. We evaluated the
relationship between erythropoietin concentrations and neurodevelopmental outcome in
extremely low birth weight infants. METHODS. Preterm infants who weighed≤ 1000 g at
birth were randomly assigned to erythropoietin (400 U/kg 3 times per week) or …