Notch signaling: direct or what?
G Weinmaster - Current opinion in genetics & development, 1998 - Elsevier
G Weinmaster
Current opinion in genetics & development, 1998•ElsevierNotch signaling has been implicated in a wide variety of processes from cell-fate decisions,
tissue patterning and morphogenesis to human diseases and cancer. A model for Notch
directly regulating gene expression has been proposed and at least two signaling pathways
have been identified; however, the molecular mechanism (s) by which Notch signaling
produces so many outcomes remains unclear.
tissue patterning and morphogenesis to human diseases and cancer. A model for Notch
directly regulating gene expression has been proposed and at least two signaling pathways
have been identified; however, the molecular mechanism (s) by which Notch signaling
produces so many outcomes remains unclear.
Notch signaling has been implicated in a wide variety of processes from cell-fate decisions, tissue patterning and morphogenesis to human diseases and cancer. A model for Notch directly regulating gene expression has been proposed and at least two signaling pathways have been identified; however, the molecular mechanism(s) by which Notch signaling produces so many outcomes remains unclear.
Elsevier