[HTML][HTML] The high molecular weight urinary matrix metalloproteinase (MMP) activity is a complex of gelatinase B/MMP-9 and neutrophil gelatinase-associated lipocalin …
L Yan, N Borregaard, L Kjeldsen, MA Moses - Journal of Biological …, 2001 - ASBMB
Detection of matrix metalloproteinase (MMP) activities in the urine from patients with a
variety of cancers has been closely correlated to disease status. Among these activities, the
presence of a group of high molecular weight (HMW) MMPs independently serves as a
multivariate predictor of the metastatic phenotype (1). The identity of these HMW MMP
activities has remained unknown despite their novelty and their potentially important
applications in non-invasive cancer diagnosis and/or prognosis. Here, we report the …
variety of cancers has been closely correlated to disease status. Among these activities, the
presence of a group of high molecular weight (HMW) MMPs independently serves as a
multivariate predictor of the metastatic phenotype (1). The identity of these HMW MMP
activities has remained unknown despite their novelty and their potentially important
applications in non-invasive cancer diagnosis and/or prognosis. Here, we report the …