Maternal use of antipsychotics in early pregnancy and delivery outcome

M Reis, B Källén - Journal of clinical psychopharmacology, 2008 - journals.lww.com
M Reis, B Källén
Journal of clinical psychopharmacology, 2008journals.lww.com
The effect of various antipsychotics during pregnancy has repeatedly been studied, but for
most atypical antipsychotics, only little information is available. We identified from the
Swedish Medical Birth Register 2908 women who had reported the use of any antipsychotic
or lithium in early pregnancy and studied malformation rates with data also from the Register
of Congenital Malformations and the Hospital Discharge Register. Comparisons were made
with all births (n= 958,729) after adjustment for some confounders. Risks were expressed as …
Abstract
The effect of various antipsychotics during pregnancy has repeatedly been studied, but for most atypical antipsychotics, only little information is available. We identified from the Swedish Medical Birth Register 2908 women who had reported the use of any antipsychotic or lithium in early pregnancy and studied malformation rates with data also from the Register of Congenital Malformations and the Hospital Discharge Register. Comparisons were made with all births (n= 958,729) after adjustment for some confounders. Risks were expressed as odds ratios (ORs).
Lippincott Williams & Wilkins