Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation
F Witte, J Dokas, F Neuendorf, S Mundlos… - Gene Expression …, 2009 - Elsevier
Wnt signalling plays important roles in patterning and outgrowth of the vertebrate limb.
Different mutations in Wnt genes, their antagonists or (co-) receptors result in patterning and
outgrowth defects as well as chondrocyte and bone phenotypes in mouse and human.
Understanding Wnt activity during mouse limb development and chondrogenesis requires a
temporal and spatial overview of Wnt signalling key factor expression. Here we present a
comparative expression analysis of all 19 Wnt genes and their major secreted antagonists of …
Different mutations in Wnt genes, their antagonists or (co-) receptors result in patterning and
outgrowth defects as well as chondrocyte and bone phenotypes in mouse and human.
Understanding Wnt activity during mouse limb development and chondrogenesis requires a
temporal and spatial overview of Wnt signalling key factor expression. Here we present a
comparative expression analysis of all 19 Wnt genes and their major secreted antagonists of …