Intracellular replication of Leishmania tropica in mouse peritoneal macrophages: amastigote infection of resident cells and inflammatory exudate macrophages
AH Fortier, DL Hoover, CA Nacy - Infection and immunity, 1982 - Am Soc Microbiol
AH Fortier, DL Hoover, CA Nacy
Infection and immunity, 1982•Am Soc MicrobiolC3HeB/FeJ peritoneal exudate cells elicited by a variety of sterile inflammatory agents were
exposed to Leishmania tropica amastigotes in vitro. Cytochemical characterization of cells
that contained intracellular parasites suggested that young, peroxidase-positive
macrophages were more susceptible to infection by amastigotes than more mature cells.
Replication of the parasite in these younger cells, however, was similar to that observed in
resident peritoneal macrophages.
exposed to Leishmania tropica amastigotes in vitro. Cytochemical characterization of cells
that contained intracellular parasites suggested that young, peroxidase-positive
macrophages were more susceptible to infection by amastigotes than more mature cells.
Replication of the parasite in these younger cells, however, was similar to that observed in
resident peritoneal macrophages.
C3HeB/FeJ peritoneal exudate cells elicited by a variety of sterile inflammatory agents were exposed to Leishmania tropica amastigotes in vitro. Cytochemical characterization of cells that contained intracellular parasites suggested that young, peroxidase-positive macrophages were more susceptible to infection by amastigotes than more mature cells. Replication of the parasite in these younger cells, however, was similar to that observed in resident peritoneal macrophages.
American Society for Microbiology