T-box transcription factor TBX20 mutations in Chinese patients with congenital heart disease

C Liu, A Shen, X Li, W Jiao, X Zhang, Z Li - European journal of medical …, 2008 - Elsevier
Despite animal studies having demonstrated that Tbx20 is essential for heart development,
few studies have been conducted about TBX20 and congenital heart disease (CHD) in
humans. Recently two TBX20 mutations have been associated with human heart defects in
two Caucasian families, but TBX20 mutations underlying the more common isolated forms of
CHD are still unknown. To explore this question and to analyze the association between
TBX20 and susceptibility to CHD 203 Chinese patients with a variety of predominantly …