Myotoxic phospholipases A2 and the regeneration of skeletal muscles

JB Harris - Toxicon, 2003 - Elsevier
The review explains why the myotoxic phospholipases A2 and cardiotoxins are such
important tools in the study of the regeneration and maturation of mammalian skeletal
muscle. The role of satellite cells as precursors of cell-based regeneration is discussed and
recent controversies on the origin of myogenic cells involved in the regeneration of mature
skeletal muscle are addressed. This is followed by discussions of sarcomere reconstruction,
myosin and sarcoplasmic reticulum ATPase expression, the electrophysiological properties …