[PDF][PDF] Fas function and tumor progression: use it and lose it
LB Owen-Schaub - Cancer Cell, 2002 - cell.com
LB Owen-Schaub
Cancer Cell, 2002•cell.comFas function and tumor progression: Use it and lose it Page 1 CANCER CELL : AUGUST 2002
95 PREVIEWS Slamon, DJ, Leyland-Jones, B., Shak, S., Fuchs, H., Paton, V., Bajamonde, A.,
Fleming, T., Eiermann, W., Wolter, J., Pegram, M., et al. (2001). N. Engl. J. Med. 344, 783–792.
Vogel, CL, Cobleigh, MA, Tripathy, D., Gutheil, JC, Harris, LN, Fehrenbacher, L., Slamon, DJ,
Murphy, M., Novotny, WF, Shak, S., et al. (2002). J. Clin. Oncol. 20, 719–726. Yarden, Y., and
Sliwkowski, M. (2001). Nat. Rev. Mol. Cell Biol. 2, 127–137. Imbalanced rates of apoptosis …
95 PREVIEWS Slamon, DJ, Leyland-Jones, B., Shak, S., Fuchs, H., Paton, V., Bajamonde, A.,
Fleming, T., Eiermann, W., Wolter, J., Pegram, M., et al. (2001). N. Engl. J. Med. 344, 783–792.
Vogel, CL, Cobleigh, MA, Tripathy, D., Gutheil, JC, Harris, LN, Fehrenbacher, L., Slamon, DJ,
Murphy, M., Novotny, WF, Shak, S., et al. (2002). J. Clin. Oncol. 20, 719–726. Yarden, Y., and
Sliwkowski, M. (2001). Nat. Rev. Mol. Cell Biol. 2, 127–137. Imbalanced rates of apoptosis …
Abstract
Recent studies have provided evidence that Fas and FasL interactions are important in the control of malignant disease and that changes in the level of Fas expression can determine immune escape and therapeutic responses.
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