Seizure after infusion of aminocaproic acid

SE Feffer, HR Parray, DW Westring - JAMA, 1978 - jamanetwork.com
AMINOCAPROIC acid is a useful agent in the management of hemophilia, particularly
following extensive dental manipulations. The drug is widely used, in large measure
because toxic reactions, including gastrointenstinal disturbances, dizziness, tinnitus,
malaise, headache, rash, and conjunctival and nasal suffusion, are mild and rarely
encountered. We report the case of a patient who experienced several of these side effects
after aminocaproic acid infusion, then promptly progressed to a grand mal seizure, a toxic …