[HTML][HTML] Permeability properties of tumor surrogate blood vessels induced by VEGF-A
JA Nagy, D Feng, E Vasile, WH Wong, SC Shih… - Laboratory …, 2006 - Elsevier
Malignant tumors generate new blood vessels by secreting growth factors, particularly
members of the vascular permeability factor/vascular endothelial growth factor (VPF/VEGF)
family. Overall, the new blood vessels that form are hyperpermeable to plasma proteins, a
property that is thought to be important for generating new stroma. However, tumor blood
vessels are structurally heterogeneous and include microvessels of at least the following
distinct types: mother vessels (MV), glomeruloid microvascular proliferations (GMP), arterio …
members of the vascular permeability factor/vascular endothelial growth factor (VPF/VEGF)
family. Overall, the new blood vessels that form are hyperpermeable to plasma proteins, a
property that is thought to be important for generating new stroma. However, tumor blood
vessels are structurally heterogeneous and include microvessels of at least the following
distinct types: mother vessels (MV), glomeruloid microvascular proliferations (GMP), arterio …