Morphological differentiation of implanted brown and white fats

L Ferren - Transactions of the Kansas Academy of Science (1903 …, 1966 - JSTOR
L Ferren
Transactions of the Kansas Academy of Science (1903-), 1966JSTOR
BF is rich in blood vessels and nerves. Cytologically its cells contain a central nucleus, many
lipid droplets (multilocular) and numerous mitochondria. It has been found that BF colntains
50-609o water and that 60-709 of the dry material is lipid, as compared to the 90% lipid
found in white fat (Smalley and Dryer, 1966). Heat production in BF has been related to its
nerve supply. It has been noted that xylocaine applied to the nerves supplying brown fat
stopped heat production in interscapular and cervical deposits (Smith, 1964). The present …
BF is rich in blood vessels and nerves. Cytologically its cells contain a central nucleus, many lipid droplets (multilocular) and numerous mitochondria. It has been found that BF colntains 50-609o water and that 60-709 of the dry material is lipid, as compared to the 90% lipid found in white fat (Smalley and Dryer, 1966). Heat production in BF has been related to its nerve supply. It has been noted that xylocaine applied to the nerves supplying brown fat stopped heat production in interscapular and cervical deposits (Smith, 1964). The present investigation involves a study of brown and white fats in the absence of normal nerve supplies. Complete denervation was achieved by removal of BF from the scapular region and implanting it into a neutral site.
Experimental Forty mice were used. A segment of brown fat was removed frolir the interscapular lobe and inserted under the kidney capsule. The samP method was, employed to denervate white fat. Representative sections cs tissues were preserved at the time of implantation. These provided th-
JSTOR