Behavioral and autonomic correlates of the tactile evoked allodynia produced by spinal glycine inhibition: effects of modulatory receptor systems and excitatory amino …
TL Yaksh - Pain, 1989 - Elsevier
Intrathecal administration of glycine (strychnine) or GABA (bicuculline) but not opioid
(naloxone), adrenergic (phentolamine) or serotonin (methysergide) receptor antagonists
resulted in a dose-dependent organized agitation response to light tactile stimulation. This
effect was maximally evoked by oscillating but not continuous stimulation applied to a
dermatome corresponding to the levels of spinal cord acted upon by the intrathecal
antagonist. Similar results were observed in chloralose-urethane anesthetized rats in which …
(naloxone), adrenergic (phentolamine) or serotonin (methysergide) receptor antagonists
resulted in a dose-dependent organized agitation response to light tactile stimulation. This
effect was maximally evoked by oscillating but not continuous stimulation applied to a
dermatome corresponding to the levels of spinal cord acted upon by the intrathecal
antagonist. Similar results were observed in chloralose-urethane anesthetized rats in which …
