Cyclosporin A does not protect the disruption of the inner mitochondrial membrane potential induced by potassium ionophores in intact K562 cells
LF Marques-Santos, VM Coqueiro… - Cell biology …, 2006 - Elsevier
Mitochondrial dysfunction has been widely associated with programmed cell death. Studies
of intact cells are important for the understanding of the process of cell death and its relation
to mitochondrial physiology. Using cytofluorometric approaches we studied the
mitochondrial behavior in an erythroleukemic cell line. The effects of protonophore carbonyl
cyanide m-chlorophenylhydrazone (CCCP), potassium exchanger (nigericin), potassium
ionophore (valinomycin), Na+ K+-ATPase inhibitor (ouabain) and mitochondrial permeability …
of intact cells are important for the understanding of the process of cell death and its relation
to mitochondrial physiology. Using cytofluorometric approaches we studied the
mitochondrial behavior in an erythroleukemic cell line. The effects of protonophore carbonyl
cyanide m-chlorophenylhydrazone (CCCP), potassium exchanger (nigericin), potassium
ionophore (valinomycin), Na+ K+-ATPase inhibitor (ouabain) and mitochondrial permeability …
