[HTML][HTML] Physiology of cholangiocytes
JH Tabibian, AI Masyuk, TV Masyuk… - Comprehensive …, 2013 - ncbi.nlm.nih.gov
JH Tabibian, AI Masyuk, TV Masyuk, SP O'Hara, NF LaRusso
Comprehensive Physiology, 2013•ncbi.nlm.nih.govCholangiocytes are epithelial cells that line the intra-and extrahepatic ducts of the biliary
tree. The main physiologic function of cholangiocytes is modification of hepatocyte-derived
bile, an intricate process regulated by hormones, peptides, nucleotides, neurotransmitters,
and other molecules through intracellular signaling pathways and cascades. The
mechanisms and regulation of bile modification are reviewed herein.
tree. The main physiologic function of cholangiocytes is modification of hepatocyte-derived
bile, an intricate process regulated by hormones, peptides, nucleotides, neurotransmitters,
and other molecules through intracellular signaling pathways and cascades. The
mechanisms and regulation of bile modification are reviewed herein.
Abstract
Cholangiocytes are epithelial cells that line the intra-and extrahepatic ducts of the biliary tree. The main physiologic function of cholangiocytes is modification of hepatocyte-derived bile, an intricate process regulated by hormones, peptides, nucleotides, neurotransmitters, and other molecules through intracellular signaling pathways and cascades. The mechanisms and regulation of bile modification are reviewed herein.
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