Atopic dermatitis

DYM Leung, T Bieber - The Lancet, 2003 - thelancet.com
DYM Leung, T Bieber
The Lancet, 2003thelancet.com
Atopic dermatitis is a highly pruritic chronic inflammatory skin disorder affecting 10–20% of
children worldwide. Symptoms can persist or begin in adulthood. It is also the most common
cause of occupational skin disease in adults. This disease results from an interaction
between susceptibility genes, the host's environment, pharmacological abnormalities, skin
barrier defects, and immunological factors. New management approaches have evolved
from advances in our understanding of the pathobiology of this common skin disorder.
Summary
Atopic dermatitis is a highly pruritic chronic inflammatory skin disorder affecting 10–20% of children worldwide. Symptoms can persist or begin in adulthood. It is also the most common cause of occupational skin disease in adults. This disease results from an interaction between susceptibility genes, the host's environment, pharmacological abnormalities, skin barrier defects, and immunological factors. New management approaches have evolved from advances in our understanding of the pathobiology of this common skin disorder.
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