[HTML][HTML] RNAi: the nuts and bolts of the RISC machine
W Filipowicz - Cell, 2005 - cell.com
W Filipowicz
Cell, 2005•cell.comResearch on RNA interference and microRNA pathways continues to accelerate.
Combinations of biochemical, genetic, and structural approaches are providing new insights
into the mechanism by which small,∼ 21 nt long RNAs find their way into the RISC effector
complexes and how the RISCs execute their mission of RNA-guided posttranscriptional
gene silencing.
Combinations of biochemical, genetic, and structural approaches are providing new insights
into the mechanism by which small,∼ 21 nt long RNAs find their way into the RISC effector
complexes and how the RISCs execute their mission of RNA-guided posttranscriptional
gene silencing.
Research on RNA interference and microRNA pathways continues to accelerate. Combinations of biochemical, genetic, and structural approaches are providing new insights into the mechanism by which small, ∼21 nt long RNAs find their way into the RISC effector complexes and how the RISCs execute their mission of RNA-guided posttranscriptional gene silencing.
cell.com