Differential regenerative ability of sensory and motor neurons
M Cheah, JW Fawcett, B Haenzi - Neuroscience Letters, 2017 - Elsevier
M Cheah, JW Fawcett, B Haenzi
Neuroscience Letters, 2017•ElsevierAfter injury, the adult mammalian central nervous system (CNS) lacks long-distance axon
regeneration. This review discusses the similarities and differences of sensory and motor
neurons, seeking to understand how to achieve functional sensory and motor regeneration.
As these two types of neurons respond differently to axotomy, growth environment and
treatment, the future challenge will be on how to achieve full recovery in a way that allows
regeneration of both types of fibres simultaneously.
regeneration. This review discusses the similarities and differences of sensory and motor
neurons, seeking to understand how to achieve functional sensory and motor regeneration.
As these two types of neurons respond differently to axotomy, growth environment and
treatment, the future challenge will be on how to achieve full recovery in a way that allows
regeneration of both types of fibres simultaneously.
Abstract
After injury, the adult mammalian central nervous system (CNS) lacks long-distance axon regeneration. This review discusses the similarities and differences of sensory and motor neurons, seeking to understand how to achieve functional sensory and motor regeneration. As these two types of neurons respond differently to axotomy, growth environment and treatment, the future challenge will be on how to achieve full recovery in a way that allows regeneration of both types of fibres simultaneously.
Elsevier