The formation of new blood vessels, uncontrolled cell expansions and invasions are the
common feature of cancer, neovascular inflammatory and ocular diseases, such as age-
related macular degeneration (AMD). Short interfering RNA (siRNA) and short-hairpin RNA
(shRNA) have recently helped extend our understanding of the mechanisms regulating
angiogenesis and tumor developments. Moreover, the early success of these tools has
reinforced the therapeutic hopes of preventing endogenous or exogenous gene translation …