[HTML][HTML] Effects of fatty acids on apolipoprotein B secretion by McArdle RH-7777 rat hepatoma cells
JD Sparks, HL Collins, I Sabio, MP Sowden… - … et Biophysica Acta (BBA …, 1997 - Elsevier
The effect of oleic acid (OA), stearic acid (SA) and elaidic acid (EA) on cellular and secreted
apolipoprotein (apo) B was examined in McArdle RH-7777 (McArdle) hepatoma cells and in
primary rat hepatocytes. Apo B secretion by McArdle cells was significantly inhibited by 20%
in 8 h incubations in medium containing EA and SA and by 50% in medium containing OA.
In contrast, apo B secretion and cellular apo B of primary rat hepatocytes was relatively
unaffected by incubations in medium containing fatty acids. Both B100 and B48 secretion in …
apolipoprotein (apo) B was examined in McArdle RH-7777 (McArdle) hepatoma cells and in
primary rat hepatocytes. Apo B secretion by McArdle cells was significantly inhibited by 20%
in 8 h incubations in medium containing EA and SA and by 50% in medium containing OA.
In contrast, apo B secretion and cellular apo B of primary rat hepatocytes was relatively
unaffected by incubations in medium containing fatty acids. Both B100 and B48 secretion in …