Nonalcoholic steatohepatitis, insulin resistance, and metabolic syndrome: further evidence for an etiologic association
G Pagano, G Pacini, G Musso, R Gambino, F Mecca… - Hepatology, 2002 - Elsevier
This study aims to determine the presence of the components of the metabolic syndrome in
primary nonalcoholic steatohepatitis (NASH) and to assess the role of liver disease in the
genesis of peripheral hyperinsulinemia. Nineteen patients (18 men and 1 woman; mean
age,±SD, 38±10 years; body mass index [BMI], 26±2 kg/m2) with histologic evidence of
NASH were enrolled; 19 age-and sex-matched normal subjects were investigated as
controls. Plasma glucose, insulin, and C-peptide levels were measured during an oral …
primary nonalcoholic steatohepatitis (NASH) and to assess the role of liver disease in the
genesis of peripheral hyperinsulinemia. Nineteen patients (18 men and 1 woman; mean
age,±SD, 38±10 years; body mass index [BMI], 26±2 kg/m2) with histologic evidence of
NASH were enrolled; 19 age-and sex-matched normal subjects were investigated as
controls. Plasma glucose, insulin, and C-peptide levels were measured during an oral …