Association of dimethylguanidino valeric acid with partial resistance to metabolic health benefits of regular exercise

JM Robbins, M Herzig, J Morningstar… - JAMA …, 2019 - jamanetwork.com
Importance Metabolic responses to exercise training are variable. Metabolite profiling may
aid in the clinical assessment of an individual's responsiveness to exercise interventions.
Objective To investigate the association between a novel circulating biomarker of hepatic fat,
dimethylguanidino valeric acid (DMGV), and metabolic health traits before and after 20
weeks of endurance exercise training. Design, Setting, and Participants This study involved
cross-sectional and longitudinal analyses of the Health, Risk Factors, Exercise Training, and …