Levodopa and levoamphetamine: a crossover study in young schizophrenic children.

M Campbell, AM Small, PJ Collins… - Current Therapeutic …, 1976 - psycnet.apa.org
M Campbell, AM Small, PJ Collins, E Friedman, R David, N Genieser
Current Therapeutic Research, 1976psycnet.apa.org
Compared the effects of levodopa and levoamphetamine in a double-blind study with 12 3-6
yr old schizophrenic inpatients. Optimal daily doses of levodopa ranged from 900 to 2,250
mg/day, those of levoamphetamine from 3.5 to 42 mg/day. Although improvements on
levodopa did not reach statistical significance, on the basis of nonblind ratings and informal
reports of blind staff and parents, levodopa merits further exploration in preschool psychotic
children, chiefly because of its stimulating behavioral effects. Levoamphetamine yielded …
Abstract
Compared the effects of levodopa and levoamphetamine in a double-blind study with 12 3-6 yr old schizophrenic inpatients. Optimal daily doses of levodopa ranged from 900 to 2,250 mg/day, those of levoamphetamine from 3.5 to 42 mg/day. Although improvements on levodopa did not reach statistical significance, on the basis of nonblind ratings and informal reports of blind staff and parents, levodopa merits further exploration in preschool psychotic children, chiefly because of its stimulating behavioral effects. Levoamphetamine yielded poor results.(42 ref)(PsycInfo Database Record (c) 2023 APA, all rights reserved)
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