Studies on 5-hydroxyindole metabolism in autistic and other mentally retarded children
RJ Schain, DX Freedman - The Journal of pediatrics, 1961 - Elsevier
RJ Schain, DX Freedman
The Journal of pediatrics, 1961•ElsevierAspects of 5-hydroxyindole metabolism have been studied in some groups of mentally
retarded children. Six of 23 children with the diagnosis of infantile autism had consistently
elevated blood 5-HT levels. The mean level of blood 5-HT of other severely retarded
children was higher than that of the mildly retarded group. No specific clinical signs could be
found in these children.
retarded children. Six of 23 children with the diagnosis of infantile autism had consistently
elevated blood 5-HT levels. The mean level of blood 5-HT of other severely retarded
children was higher than that of the mildly retarded group. No specific clinical signs could be
found in these children.
Summary
Aspects of 5-hydroxyindole metabolism have been studied in some groups of mentally retarded children. Six of 23 children with the diagnosis of infantile autism had consistently elevated blood 5-HT levels. The mean level of blood 5-HT of other severely retarded children was higher than that of the mildly retarded group. No specific clinical signs could be found in these children.
Elsevier