Generalized gastrointestinal polyposis: an unusual syndrome of polyposis, pigmentation, alopecia and onychotrophia
LW Cronkhite Jr, WJ Canada - New England Journal of Medicine, 1955 - Mass Medical Soc
LW Cronkhite Jr, WJ Canada
New England Journal of Medicine, 1955•Mass Medical SocTWO cases are reported below in which the presenting complaints were disturbances in
gastrointestinal function, pigmentation of the skin, alopecia and atrophy of the fingernails
and toenails. In each case the underlying pathologic process seemed to be generalized
gastrointestinal polyposis in which virtually the entire gastrointestinal mucosa was replaced
by polypoid lesions. These cases are of interest in that they probably differ in nature from
other syndromes that relate polyposis to pigmentation of the skin. Case Reports CASE 1. ES …
gastrointestinal function, pigmentation of the skin, alopecia and atrophy of the fingernails
and toenails. In each case the underlying pathologic process seemed to be generalized
gastrointestinal polyposis in which virtually the entire gastrointestinal mucosa was replaced
by polypoid lesions. These cases are of interest in that they probably differ in nature from
other syndromes that relate polyposis to pigmentation of the skin. Case Reports CASE 1. ES …
TWO cases are reported below in which the presenting complaints were disturbances in gastrointestinal function, pigmentation of the skin, alopecia and atrophy of the fingernails and toenails. In each case the underlying pathologic process seemed to be generalized gastrointestinal polyposis in which virtually the entire gastrointestinal mucosa was replaced by polypoid lesions. These cases are of interest in that they probably differ in nature from other syndromes that relate polyposis to pigmentation of the skin.
Case Reports
CASE 1. E.S. (B.M. 733228), a 42-year-old single female bookkeeper, was first seen in March, 1951, because of nausea, vomiting and diarrhea of . . .
The New England Journal Of Medicine