Claudin profiling in the mouse during postnatal intestinal development and along the gastrointestinal tract reveals complex expression patterns
JL Holmes, CM Van Itallie, JE Rasmussen… - Gene Expression …, 2006 - Elsevier
Members of the claudin protein family are key regulators of tight junction selectivity and are
implicated in influencing development and cellular differentiation in the intestine and other
tissues. The goal of the present study was to profile claudin gene expression and protein
location during postnatal development of the mouse jejunum and in the adult mouse gut
from duodenum to distal colon as a first step in understanding both normal claudin function
and the pathologic implications of altered expression patterns. The relative expression of …
implicated in influencing development and cellular differentiation in the intestine and other
tissues. The goal of the present study was to profile claudin gene expression and protein
location during postnatal development of the mouse jejunum and in the adult mouse gut
from duodenum to distal colon as a first step in understanding both normal claudin function
and the pathologic implications of altered expression patterns. The relative expression of …
