Publisher Summary Claudins are the main constituents of tight junction (TJ) filaments, and
their function is regulated by several posttranslational modifications including
phosphorylation, palmitoylation, and signaling through cytokines, prostaglandins, and
hormones. This chapter describes the putative phosphorylation sites present in the claudin
family of proteins and analyze those phosphorylations that trigger a specific cellular
response. The chapter also describes how cytokines, transforming growth factor β …