[HTML][HTML] Myocyte Enhancer Factor 2 (MEF2)-Binding Site Is Required forGLUT4 Gene Expression in Transgenic Mice: REGULATION OF MEF2 DNA BINDING …

MV Thai, S Guruswamy, KT Cao, JE Pessin… - Journal of Biological …, 1998 - ASBMB
We have previously demonstrated that important regulatory elements responsible for
regulated expression of the humanGLUT4 promoter are located between− 1154 and− 412
relative to transcription initiation (Olson, AL, and Pessin, JE (1995) J. Biol. Chem. 270,
23491–23495). Through further analysis of this promoter regulatory region, we have
identified a perfectly conserved myocyte enhancer factor 2 (MEF2)-binding domain (-
CTAAAAATAG-) that is necessary, but not sufficient, to support tissue-specific expression of …