The time course of expression of MMP-9 and MMP-2 and corresponding aneurysm growth. WT mouse aortae were incubated with CaCl2 or NaCl. Three days, 1 week, and 2, 3, and 4 weeks after treatment, the aortic diameters were measured and mice were sacrificed. (a) CaCl2-treated mice; (b) NaCl-treated mice (control). (c) Aortic diameter increases in CaCl2-treated mice at indicated time points. (d) H&E staining of CaCl2-treated mouse aortic section, showing a significant inflammatory infiltrate at 3 days.